Batchelor Lab


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My lab seeks to develop an integrated, system-level understanding of stress responses at multiple scales -- from individual cells to whole organisms. Much of our research focuses on cell stress responses mediated by the tumor suppressor protein p53, as well as other signaling pathways important in cancer prevention and development. We use a combination of time-lapse microscopy, single cell analysis, and computational modeling to understand how cell fate is controlled in individual cells responding to stress conditions and damage. We use this knowledge to bring novel insights into how stress responses operate in healthy conditions, as well as how they are disrupted in pathological conditions.